top of page
Uric Acid


This procedure is a modification of the Fossati method, which uses coupled enzyme reactions to convert uric acid to allantoin and hydrogen peroxide. The hydrogen peroxide then reacts with a dye and the amount of the dye formed is proportional to the amount of uric acid in the sample.

Test Utility

Uric acid measurements are used in the diagnosis and treatment of renal and metabolic disorders.

Specimen Collection and Preparation

Serum or plasma sample in the following tubes:

  • Serum separator tube (gold or tiger top)

  • Heparin (green top)

Specimen Storage and Stability

Store serum or plasma at the following temperatures:

  • Room temperature: Not indicated

  • Refrigerated: 2°C to 8°C up to 5 days

  • Frozen: -15°C or lower for up to 6 months. Thaw samples only once

Specimen Rejection

  • Insufficient sample volume

  • Potassium oxalate/sodium fluoride plasma

  • Sample not stored at proper temperature

  • Frozen whole blood

  • Severely hemolyzed samples

  • Severely lipemic specimens

  • Specimen labeled incorrectly or not labeled

Reference Pages


Monday – Saturday

Result available within 24 hours of receipt in laboratory

NOTE: Specimens are refrigerated (2-8°) for 7 days before disposal

STAT results available within 2 hours of receipt in the laboratory


Vibra Health Laboratory

1307- A, Allen Dr

Troy, MI 48083

(248) 846-0663

bottom of page