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Procalcitonin (PCT)

Methodology

The Procalcitonin assay is a paramagnetic, chemiluminescent immunoassay

Test Utility

This test is used as an early indicator to identify patients that have sepsis as well as to monitor patient response to antibiotic therapy. PCT is a biomarker specific for bacterial infections where levels are increased in patients with a systemic inflammatory response due to bacterial endotoxins and inflammatory cytokines.

Specimen Collection and Preparation

Serum or plasma sample in the following tubes:

  • Serum separator tube (gold or tiger top)

  • EDTA (lavender top) and Lithium Heparin (green top)

Specimen Storage and Stability

Store serum or plasma at the following temperatures:

  • Room temperature for up to 16 hours

  • Refrigerated: 2°C to 8°C for up to 48 hours

  • Frozen: -20°C or lower for up to 75 days

Specimen Rejection

  • Insufficient sample volume

  • Sample not stored at proper temperature

  • Frozen whole blood

  • Severely hemolyzed samples

  • Severely lipemic specimens

  • Specimen labeled incorrectly or not labeled

Reference Pages

Performed

Monday – Saturday

Result available within 24 hours of receipt in laboratory

NOTE: Specimens are refrigerated (2-8°) for 7 days before disposal

Contacts

Vibra Health Laboratory

1307- A, Allen Dr

Troy, MI 48083

(248) 846-0663

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