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Hepatitis B Virus Core IgM Antibody (HBc IgM)


The HBc IgM assay is an IgM capture immunoassay that uses a 2-step format to identify antibody-antigen complexes that are formed if HBV is present.

Test Utility

This test is used to determine active infection to HBV by looking for antibodies to the viral central core and surrounding envelope.

Specimen Collection and Preparation

Serum or plasma sample in the following tubes:

  • Serum separator tube (gold or tiger top)

  • EDTA (lavender top) and Lithium/Sodium Heparin (green top)

Specimen Storage and Stability

  • Store serum or plasma at the following temperatures:

  • Room temperature: Up to 8 hours

  • Refrigerated: 2°C to 8°C for up to 2 days

  • Frozen: -20°C or lower: Samples should not be thawed more than 4 times.

Thoroughly mix and centrifuge thawed samples for 2 minutes before using.

Specimen Rejection

  • Insufficient sample volume

  • Sample not stored at proper temperature

  • Frozen whole blood

  • Severely hemolyzed samples

  • Severely lipemic specimens

  • Specimen labeled incorrectly or not labeled

Reference Pages


Monday – Saturday

Result available within 24 hours of receipt in laboratory

NOTE: Specimens are refrigerated (2-8°) for 7 days before disposal


Vibra Health Laboratory

1307- A, Allen Dr

Troy, MI 48083

(248) 846-0663

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