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This is a modification of the Fabiny and Ertingshausen reaction where a yellow-orange complex is formed when creatinine reacts with picric acid at an alkaline pH.

Test Utility

This test measures creatinine, a waste product made by your muscles, that is filtered and removed through the kidneys. Creatinine can be used as an indicator of kidney function where an increase in creatine may indicate a problem with the kidneys.

Specimen Collection and Preparation

Serum or plasma sample in the following tubes:

  • Serum separator tube (gold or tiger top)

  • Lithium Heparin (green top)

Specimen Storage and Stability

Store serum or plasma at the following temperatures:

  • Refrigerated: 2°C to 8°C for up to 7 days

  • Frozen: -20°C or lower indefinitely

Specimen Rejection

  • Insufficient sample volume

  • Sample not stored at proper temperature

  • Frozen whole blood

  • Severely hemolyzed samples

  • Severely lipemic specimens

  • Specimen labeled incorrectly or not labeled

Reference Pages


Monday – Saturday

Result available within 24 hours of receipt in laboratory

NOTE: Specimens are refrigerated (2-8°) for 7 days before disposal

STAT results available within 2 hours of receipt in the laboratory


Vibra Health Laboratory

1307- A, Allen Dr

Troy, MI 48083

(248) 846-0663

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